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IVF: WTF?


If you are exploring IVF as your path to parenthood, then you may be feeling overwhelmed and confused. Patients are quite often bombarded with information and don't know where to start. So, here is your step by step guide to IVF.



In vitro fertilization (IVF) is a complex reproductive technology that helps couples with fertility issues conceive a child. The process typically involves several key stages. Here are the key stages of IVF:


1. Ovarian Stimulation: The first step of IVF involves the administration of fertility medications to the woman to stimulate her ovaries to produce multiple mature eggs. Normally, a woman produces a single egg each menstrual cycle, but with ovarian stimulation, several eggs can be developed simultaneously.


2. Egg Retrieval: Once the eggs have matured, a minor surgical procedure called egg retrieval or follicular aspiration is performed. Under ultrasound guidance, a thin needle is inserted through the vagina to reach the ovaries and collect the eggs from the follicles.


3. Sperm Collection: On the day of egg retrieval, the male partner or a sperm donor provides a semen sample. The sperm is then processed to isolate healthy and motile sperm for the fertilization process.


4. Fertilization: In the laboratory, the collected eggs and sperm are combined in a controlled environment to allow fertilization to occur. There are two primary methods of fertilization used in IVF: conventional insemination, where sperm is placed in the same dish as the eggs, or intracytoplasmic sperm injection (ICSI), where a single sperm is injected directly into each mature egg.


5. Embryo Culture: After fertilization, the resulting embryos are cultured in a laboratory for a few days. During this time, they are monitored for their growth and development.


6. Embryo Transfer: Once the embryos have reached a suitable stage of development, one or more embryos are selected for transfer into the woman's uterus. The transfer is typically done using a thin catheter, guided by ultrasound, to place the embryos into the uterine cavity.


7. Luteal Phase Support: After the embryo transfer, hormonal medications such as progesterone are often prescribed to support the implantation of the embryos and early pregnancy.


8. Pregnancy Test: Approximately two weeks after the embryo transfer, a blood test is conducted to determine if the IVF procedure was successful and pregnancy has been achieved.


It's important to note that the specific protocols and procedures may vary slightly depending on the fertility clinic and individual circumstances. Additionally, there may be additional optional steps such as preimplantation genetic testing (PGT) to screen embryos for genetic abnormalities before transfer.


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